In search of (un)desired side effects
Pharmaceutical researchers speak of a hit when they come across a promising substance with a desired effect in early drug discovery. Unfortunately, hits are rarely bull’s-eyes, often showing undesirable side effects that not only complicate the search for new hits, but also the subsequent development into a drug. A new study could now help to better identify one of the most frequently observed side effects already in early drug discovery, but also to find new bioactivities.
Materials provided by Max Planck Institute of Molecular Physiology. Note: Content may be edited for style and length.
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