Degrading a key cancer cell-surface protein to invigorate immune attack on tumors



Degrading a key cancer cell-surface protein to invigorate immune attack on tumors

One powerful way cancer cells defend against tumor-killing immune cells is to load up their cell surface with a protein known as PD-L1. Now a team of researchers has identified a method to degrade tumor cell-surface PD-L1, thereby making tumors susceptible to immune attack.

Materials provided by University of California – Los Angeles Health Sciences. Note: Content may be edited for style and length.




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