Researchers discover mechanism linking mutations in the ‘dark matter’ of the genome to cancer
Many sections of the non-coding region of the human genome play a key role in regulating gene activity. But the relationship between non-coding mutations and cancer risk has been a mystery. New research sheds light on that mystery, providing clues that may link mutations to epigenetic changes, and may point to potential drug targets to reduce risk for people born with certain genetic mutations.
Materials provided by Dana-Farber Cancer Institute. Note: Content may be edited for style and length.
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