Androgen receptor signaling contributes to targeted therapy resistance in melanoma



Androgen receptor signaling contributes to targeted therapy resistance in melanoma

Androgen receptor (AR) signaling affects response to BRAF/MEK inhibitor therapy in both males and females with melanoma, researchers have shown. The findings provide a new target to combat therapeutic resistance and one possible answer to why men face a poorer prognosis than women when diagnosed with melanoma.

Materials provided by University of Texas M. D. Anderson Cancer Center. Note: Content may be edited for style and length.




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