Programmed cell death in cancer cells: Overcoming resistance through paraptosis-inducing compounds
Inducing programmed cell death (PCD), such as apoptosis, is a widely used therapeutic option for the treatment of cancer. Unfortunately, many cancer cells become resistant to PCDs, and continue multiplying. In a new study, researchers have synthesized new complex-hybrid compounds named triptycene-peptide hybrids (TPHs), which successfully induced a kind of PCD known as paraptosis in Jurkat cells – -a type of lymphocytes. These paraptosis-inducing compounds may revolutionize cancer therapy in the future.
Materials provided by Tokyo University of Science. Note: Content may be edited for style and length.
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