Scientists uncover new therapeutic target for treating colorectal tumors
Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane. Further, they identify an antibody that reduces colitis severity and colonic tumor growth, highlighting the potential of DCIR as a therapeutic target.
Materials provided by Tokyo University of Science. Note: Content may be edited for style and length.
Source link aaaaa