Researchers discover new molecular driver of retinoblastoma
Despite decades of medical advances, children who develop the pediatric eye cancer retinoblastoma often lose their vision or an eye due to a lack of specific, targeted therapies and a poor molecular understanding of the cancer. Now researchers have discovered that a molecule — estrogen-related receptor gamma, or ESRRG — becomes hyperactive and promotes tumor cell survival in retinoblastoma. Blocking ESRRG, the team reported, kills retinoblastoma cells.
Materials provided by UT Southwestern Medical Center. Note: Content may be edited for style and length.
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