Researchers discover how to overcome a treatment resistance mechanism in one of the most aggressive types of breast cancer
A study has determined the role that fibroblasts, the cells that contribute to tissue formation, play in a tumor’s ability to generate resistance to the most common biological treatment for HER2. The paper demonstrates the ability of a new therapy, currently undergoing clinical trials, to promote a potent immune response by binding to the fibroblasts, enabling it to overcome resistance to anti-HER2 therapy in tumors with this cancer cell protection mechanism.
Materials provided by IMIM (Hospital del Mar Medical Research Institute). Note: Content may be edited for style and length.
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