Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies
Researchers have recently shown that vitamin C improves the immunogenic properties of dendritic cells, in vitro. Results recently made public show that treating the cells with vitamin C leads to a more consistent activation of genes involved in the immune response, mainly through DNA demethylation, a kind of epigenetic reprogramming. This discovery may be useful to generate more potent dendritic cell-based therapies in the future.
Materials provided by Josep Carreras Leukaemia Research Institute. Note: Content may be edited for style and length.
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