Potential genetic variants linked to increased cancer risk in children with birth defects
Researchers have identified several genetic variants associated with increased risk of cancer in children with non-chromosomal birth defects, such as congenital heart disease and defects of the central nervous system. While the risk of developing cancer is not as high as children with chromosomal birth defects, it is significantly higher than children with no birth defects at all, and the findings may provide a basis for early detection in these understudied patients.
Materials provided by Children’s Hospital of Philadelphia. Note: Content may be edited for style and length.
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