Researchers circumvent radiation resistance in subtype of brain tumors



Researchers circumvent radiation resistance in subtype of brain tumors

Researchers have uncovered a gene that is overexpressed in mutated IDH1. Studies in human cells and a novel mouse model both show that this gene, called ZMYND8, plays a critical role in the radiation resistance. When they knocked down the gene, the glioma cells became responsive to radiation treatment.

Materials provided by Michigan Medicine – University of Michigan. Original written by Nicole Fawcett. Note: Content may be edited for style and length.




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