Study provides an explanation and potential solution for severe graft-versus-host disease
Researchers found that alterations in the gut microbiome that are linked to graft-versus-host disease severity are connected to an increase in oxygen levels in the intestine that follows immune-mediated intestinal damage. Pharmacologically reducing intestinal oxygen levels alleviated the microbial imbalance and reduced the severity of the condition in animal models.
Materials provided by Baylor College of Medicine. Note: Content may be edited for style and length.
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