Engineered E. coli delivers therapeutic nanobodies to the gut
Researchers have succeeded in developing an E. coli-based ‘smart microbe’ that secretes therapeutic payloads, including antibodies, into the gut. The genetically modified beneficial strain of bacteria blocks intestinal inflammation in a preclinical model of inflammatory bowel disease and has the potential to treat intestinal-based diseases.
Materials provided by Massachusetts General Hospital. Note: Content may be edited for style and length.
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